ALK-Negative ALCL
3 min readSep 18, 2022
--
Lessons from the Friday Unknowns
Histologic sections show fragments of lymph node involved by lymphoma. The lymphoma shows a sinusoidal infiltration pattern, and is composed of large pleomorphic cells, with irregular nuclear contours, open chromatin, visible nucleoli, and variable amounts of eosinophilic cytoplasm.