Follicular Helper T-Cell Lymphoma

Lessons From the Friday Unknowns

Sections of the needle biopsies of left retroperitoneal lymph node reveal a diffuse, abnormal lymphohistiocytic proliferation, with effacement the normal lymph node. The lymphocytes are a mixed population of small, intermediate size and large cells, with predominance of intermediate sized cells. The lymphocytes are atypical, having angulated nuclei with irregular nuclear contours and a hyperchromatic nuclear staining pattern. Histiocytes are uniformly present in high number within the lymphomatous proliferation. A…