Dec 2, 2022
2 min read
Primary Cutaneous Anaplastic Large Cell Lymphoma with IRF4/DUSP22 Rearrangement
Lessons From the Friday Unknowns
The skin biopsy shows a dense dermal infiltration with epidermotropism. The infiltrating lymphocytes ranging in size from small to medium size. The epidermis shows epidermotropism of smaller lymphocytes, few of which few are cerebriform. The neoplastic cells display irregular nuclear contours with occasional prominent nucleoli. The cytoplasm is scant to moderately abundant. Mitoses are numerous; no necrosis is noted.
