Rhabdomyosarcoma Involving Bone Marrow
Sep 21, 2021
Lessons From The Friday Unknowns
The patient is a 17 year old female with recurrent alveolar rhabdomyosarcoma.
The bone marrow biopsy shows a variably cellular bone marrow with decreased trilineage maturing hematopoesis and ~40–50% involvement by metastatic tumor cells by desmin stain. In addition, per submitted pathology report, fluorescence in situ hybridization is positive for a FOXO1 rearrangement.
Link to digital slides slides: https://bit.ly/2YQqaNJ | Slides labeled case 3